Abstract

Background & Objectives: There are many benefits associated with the laparoscopic surgery including faster recovery, shorter hospital stay and prompt return to normal activities. Although laparoscopic surgery is minimally invasive in nature but high incidence of postoperative nausea and vomiting (PONV) remains a major cause of morbidity. To prevent PONV, multimodal techniques are helpful, but not any one technique is idea to deal with this problem. This study was carried out to compare the efficacy of intraoperative high oxygen concentration in prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. The objective of this study is to observe the effectiveness of high oxygen concentration in prevention of postoperative nausea and/ or vomiting in adult females undergoing elective laparoscopic cholecystectomy. Materials & Methods: This prospective observational study was conducted at Aga Khan University and Hospital,Karachi,Pakistan.After obtaining approval from departmental review committee and ethics review committee of AKU and informed written consent,74 adult female patients ASA I and ASA II of age 18 to 40 years undergoing elective laparoscopic cholecystectomy were included in the study and all of them received 70% oxygen in air in the intraoperative period. Postoperatively patients were observed for 24 hours for any episode of nausea or vomiting, or whether the patients required any rescue antiemetic. Results: High intraoperative oxygen concentration has not significantly affect the incidence of PONV in adult female patients underwent laparoscopic cholecystectomy. During the 24 hr period, out of 74 patients, 30patients (40.54%) experience PONV and required rescue antiemetic medication and 44 patients (59.46) experience no PONV. Conclusion: This study has demonstrated that high intraoperative oxygen was not effective in prevention of postoperative nausea and vomiting in adult female patients undergoing elective laparoscopic surgery. Disclosure of Interest: None declared

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