Abstract PO-268: Investigating patient barriers to low-dose computed tomography lung cancer screenings among the African American population

Abstract

Abstract Background Lung cancer remains the leading cause of cancer death in the United States. Lung cancer screening (LCS) with Low-Dose Computerized Tomography (LDCT) has been found to reduce lung cancer mortality up to 26% and all-cause mortality by 7%. Yet, uptake of LCS is less than 4% among those eligible. African Americans (AAs) have the highest cancer mortality rate and are also more likely to die of lung cancer compared to whites. Furthermore, little research has been done to understand this groups in terms of their knowledge, awareness, and perceptions related to LCS, and the potential barriers or facilitators to LCS. Guided by the Health Believe Models, this study aims to examine the demographic, behavioral, and psychosocial profiles related to LCS in AAs, and identify the predictors to the uptake of LCS with LDCT. Methods We have recruited 200 AA patients eligible for LDCT for a case-control cohort (100 AAs who have completed a LDCT screening and 100 who did not) through the electric medical record of a safety-net hospital. We are currently conducting online and telephone surveys to collect information on participants' personal and family history, health literacy, beliefs, psychosocial factors, patient-provider relationship, knowledge of lung cancer, perception of screening and potential care cost, transportation barriers, and racial discrimination. Results We will conduct descriptive analysis of the sociodemographic characteristics and the modifiable lifestyle behaviors of the participants separately for those who completed LDCT and those who did not. We will then conduct bivariate analysis (chi-square and t-test) to compare various psychosocial and health-related factors by LDCT completion status. Finally, we will conduct binary logistic regression to examine the association between the predictors and LDCT completion. Conclusion The findings of this study will provide critical empirical evidence on the psychosocial facilitators and barriers to LDCT uptake among AAs, a vulnerable and medically underserved population. The facilitators and barriers identified in this study will be used to design both clinic-based and community-based behavioral intervention studies to promote LDCT uptake among eligible AAs. Citation Format: Alexander Nguyen, Lin Zhu, Ra'Ann Merceir, Grace X Ma, Cherie P Erkmen. Investigating patient barriers to low-dose computed tomography lung cancer screenings among the African American population [abstract]. In: Proceedings of the AACR Virtual Conference: 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2021 Oct 6-8. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr PO-268.