Abstract PO-228: Trends in uterine cancer incidence and mortality in New York City

Abstract

Abstract According to the American Cancer Society's 2020 Annual Report, uterine cancer continues to pose a serious threat to the lives of women in the United States, particularly among African-Americans. Nationally, the incidence of uterine cancers rose 1% per year from 2007 to 2016 among Caucasian women but it rose 2% each year among African-American women. Although the mortality rate increased by 2% per year from 2008 to 2017 for both African-American and Caucasian women, the survival rates are strikingly different. The 5-year relative survival rate is 84% for Caucasian women but drops to 62% for African-American women. The purpose of this study was to evaluate the local trends in uterine cancer incidence and mortality among women in New York City. Methods: Publicly available data from the New York State Cancer Registry were analyzed. We evaluated uterine cancer incidence and mortality rates between 1976 to 2016 according to race and borough. Uterine cancer incidence and mortality rates according to Hispanic ethnicity were also evaluated from 2012-2016. Results: Between 1976 and 2016, the uterine cancer incidence rate increased from 24.1 cases per 100,000 women to 31 cases per 100,000 women among Caucasian women. During the same period, the uterine cancer incidence rate more than doubled from 16 cases per 100,000 women to 34.2 per 100,000 women among Black women. By 2010, the uterine cancer incidence rate among Black women had surpassed those of their Caucasian counterparts. From 2012 to 2016, uterine cancer incidence was lower for Hispanic women (24.2 per 100,000) compared to Black and Caucasian women. However, the mortality rate (5.1 per 100,000) for Hispanic women was comparable to that of Caucasian women (5.9 per 100,000) but nearly half of that for Black women (11.3 per 100,000). Between 1976 and 2016, uterine cancer incidence rates nearly doubled in the Bronx and Kings County. Uterine cancer mortality also nearly doubled in the Bronx over the past 4 decades. Conclusion: In New York City, uterine cancer mortality and incidence rates have risen sharply among Black women. The reasons for disparities among uterine cancer patients require further investigation. They may include access to healthcare, socioeconomic status, health literacy and genetic mutations. Citation Format: Onyinye Balogun. Trends in uterine cancer incidence and mortality in New York City [abstract]. In: Proceedings of the AACR Virtual Conference: Thirteenth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2020 Oct 2-4. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(12 Suppl):Abstract nr PO-228.