Abstract PO2-29-01: POSITIVE PREDICTIVE VALUE FOR THE MALIGNANCY OF MAMMOGRAPHIC ABNORMALITIS IN A ONE-STOP CLINIC MODEL FOR BREAST CANCER IN COLOMBI

Abstract

Abstract Breast cancer (BC) is the most prevalent malignancy among women in Colombia, with the greatest incidence rate among malignancies. According to available data through the year 2020, the Colombian female population has officially documented 52,025 cases of breast cancer. This variety of cancer has emerged as the leading cause of cancer-related mortality among Colombian women. Currently, it is essential to emphasize the significance of the BI-RADS (Breast Imaging Reporting and Data System) classification as a means of categorizing patients’ risk levels based on criteria for subsequent breast pathology evaluation and diagnosis. We aimed to assess the positive predictive value of BIRADS IV and V in predicting the risk of breast cancer in the Colombian population. From September 2018 to December 2022, consecutive patients referred for breast mammography and suspected of having breast cancer underwent triple assessment of breast tumor and were included in this retrospective study. 27.937 patients were included with breast imaging report and BIRADS classification system 4 and 5. Patients with a previously diagnosed case of breast cancer and a BIRADS score of 1,2 or 3 were excluded. The positive predictive value of categories 4 and 5 was determined using histopathologic results of ultrasound- or stereotactically-guided biopsies as the gold standard. 46% of 21,442 patients had BACAF biopsies, 39% TRUCUT, and 15% stereotactic. Category 4A was found in 12,865 patients (60%) with a 7% positivity rate, 4B in 8,362 (25%) with 20%, and 4C and 5 in 3,216 (15%) with 75%. BIRADS 4 and 5 had a 20% positive predictive value, with 4,371 positive participants (31% under 49 and 69% over 50). Categories 4 - 5 were found to be beneficial for predicting the likelihood of malignancy, with categories 4C and 5 yielding the highest rates of positive results. Comparable to previous research, the PPV for malignancy in the present investigation was comparable. Citation Format: Kelly Corredor, Sara Gil, Carlos Agudelo, Clara Piedrahita, Melissa Naranjo. POSITIVE PREDICTIVE VALUE FOR THE MALIGNANCY OF MAMMOGRAPHIC ABNORMALITIS IN A ONE-STOP CLINIC MODEL FOR BREAST CANCER IN COLOMBI [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO2-29-01.