Abstract
Aims & Objectives: Enteroviruses (EV) are common pathogens. Young children are particularly prone to severe complications with EV infection. Some of them are associated with severe and fatal infections necessitating Pediatric Intensive Care Unit (PICU) admission and support. Methods We reviewed clinical outcomes of enterovirus isolation in all PICU admissions between Oct 2002 and December 2017. Specimens included nasopharyngeal aspirates, stools and cerebrospinal fluids. Results EV isolations were present in 60 of 2583 patients (2.3%). EV 71 accounted for 5% of these EV. S. pneumoniae disease (serotype 3, n=3) were present in 10%, encephalitis in 13% and asthma in 23%. Mortality associated with EV isolation was 6% and mean PICU length of stay was 6.4 days. There was no difference in PICU mortality or morbidity between infants and children >1 years of age. Conclusions EV is associated with moderate mortality, S. Pneumoniae co-infection and encephalitis in infants and older children.
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