Abstract PCCLB-16: PREVALENCE OF ACUTE KIDNEY INJURY AND ASSOCIATED FACTORS IN THE PEDIATRIC CRITICAL MEDICINE UNIT

Abstract

Aims & Objectives: To determine the prevalence of acute kidney injury (AKI) in critically ill patients admitted to the pediatric intensive care unit by KDIGO criteria. Methods Retrospective, longitudinal and observational study. Was performed in patients hospitalized in PICU from March 2015 to February 2016. Patients from 1 month to 15 years old were included. We excluded patients with previous kidney disease, malformations of the urinary tract, patients with kidney transplant, brain death, pregnancy, patients with less than 48 hours of stay, transfer to another hospital or incomplete file. The creatinine levels during the first 10 days of stay were monitored to determine which patients developed AKI by KDIGO criteria. Results The prevalence of acute kidney injury in our population was 44.9% according to KDIGO criteria. 29.4% of the cases have severe AKI (stage 2 and 3). The presence of AKI had an effect on patient mortality, approximately 10 times the mortality rate (p <0.0001). The 28-day survival in the AKI stage 3 group was significantly lower (p <0.0001). Cardiac arrest, shock and dehydration on admission or during first 72 hours was associated with the presence of AKI. Treatment with diuretics was significantly higher in patients with AKI. The RRT were performed in 0.7% of the studied population, and 50% mortality.Conclusions Cardiac arrest, shock and dehydration were the significant risk factors for our population. The presence of sepsis and respiratory failure are the main risk factor for the development of AKI.