Abstract P539: Association of Metabolic Syndrome With Angina: Results From NHANES 2009 - 2020

Abstract

Background: Metabolic syndrome (MetS) is a known risk factor for cardiovascular disease. However, there are limited data on its association with angina. We assessed the association of MetS with angina in a nationally representative sample of noninstitutionalized Americans. Methods: We combined data from five National Health and Nutrition Examination Survey (NHANES) data cycles from 2009 to 2020. We included participants aged 40 years or older. MetS was defined using the AHA/NHLBI criteria. Angina was ascertained based on the ROSE angina questionnaire. Multivariable logistic regression models adjusting for age, race, and sex were used to assess the association between MetS and angina. Results: Among the 21752 participants included in the analysis, 11381 (52.3%) met the criteria for MetS. Nine hundred and fifty-nine participants (4.4%) had angina. Angina was more prevalent among those with MetS than those without MetS (5.9% vs. 2.8%; p = <.0001). Compared with participants without MetS, Those with MetS were more than two-fold more likely to suffer from angina (adjusted Odds Ratio, 2.06; 95% CI 1.76-2.40; p = <.0001). Conclusion: From this nationally representative sample, participants aged 40 years or older with MetS were more likely to suffer from angina compared with those without MetS. Suggesting MetS as an independent risk factor of coronary artery disease.