Abstract P438: Cardio-Renal Anemia Syndrome in acute heart failure patients: An Observational data from “Gulf-CARE” Heart Failure Registry

Abstract

Aims: Cardio renal anemia syndrome is a condition (CRAS) where heart failure, anemia and renal failure co-exist. The purpose of this article is to measure and analyze the role of CRAS in acute heart failure in terms of left ventricular (LV) systolic function. Subjects & Methods: Gulf aCute heArt failuRe rEgistry (Gulf-CARE) study analyzed 5005 consecutive patients admitted with AHF to 47 hospitals in middle-eastern Gulf countries between 14 February and 14 November 2012. Out of which we analyzed the data of patients with CRAS and divided into two groups. The first group G1 that consists of CRAS patient with ejection fraction (EF) less than 40%, where the second group G2 that consists of CRAS patient with ejection fraction (EF) more than 40%. Chi-square test of independence was utilized for G1 and G2. Results: Out of total study population of 5005 patients, 26.8 % (1343) were identified as CRAS patients. Anemia was observed in 54.5% (2728/5005) and chronic kidney disease (CKD) in 45.1% (2257/5005) patients. G1 had 743 patients, and G2 had 600 patients. It was overserved that in G1, around 40.4% (300) were in NYHA Class IV, where G2 has only 28.8 % (173) with a p value=0.001. Cardiogenic shock, Intubation, and major bleeding were reported almost same in both groups. In-hospital stroke was seen more in G1 1.6% (12) when compared to GII 0.8% (5) without any statistical significance ( p =0.20). Out of total CRAS patients, 36.6% (491/1343) had dialysis. Mortality rates were almost similar in both groups 6.1% (45) in GI and 6.7% (40) in GII. Conclusions: In the setting of acute heart failure in CRAS patients LV function has no significant role in the incidence of in-hospital stroke, major bleeding and death.