Abstract P409: Mortality in Subarachnoid Hemorrhage Varies by Day and Month Within the USA

Abstract

Introduction: High mortality is associated with aneurysmal subarachnoid hemorrhage (SAH). Despite years of studies and translational research, only a few health and lifestyle factors have been found to definitively associate with an increased risk of SAH incidence and mortality. Prior studies have provided some evidence that environmental factors play a role in the incidence of SAH, but the available data is not often consistent or applicable to the United States of America (USA). Here we provide support that there is a temporal differences in SAH mortality by month of the year and day of the week. Methods: The Centers for Disease Control (CDC) and Prevention public health database (wonder.cdc.gov) was accessed. Mortality events for the years 1999-2016 were obtained for deaths attributed to SAH from a named vessel distribution with accounting for day of week and month of year as well as gender from year to year. ANOVA was used to test for differences by week or month. Results: Mortality for week day variations found no significant differences (p = 0.13) in women, while men demonstrated a significant difference (p = 0.003) with the most common day of death being Monday. Mortality for monthly variation found a significant difference (p = 0.01) in total with January being the most common month of SAH mortality. However, divided by gender women (p = 0.06) and men (p = 0.10) did not meet predefined statistical significance. Conclusion: Mortality from SAH appears to have a variation in time of day of week in men and by month for both genders but this has unclear significance at this time.