Abstract

Aim: This study was conducted to evaluate the effect of ARB/CCB combination tablet treatment considering patient-physician concordance on the patient and physician satisfaction for the hypertensive treatment. Methods: In an open-label, multicenter study, patients with insufficient hypotensive effect receiving treatment with ARB or CCB monotherapy were enrolled and their medication switched to an ARB/CCB combination tablet taken for 12 weeks. Home and clinic BP rates were evaluated at baseline and at 12 weeks. Both physicians and patients participated in satisfaction surveys concerning the treatment at baseline and at 12 weeks. Results: One hundred twelve patients were screened and 85 patients were enrolled. Significant differences were found between patient and physician rates of satisfaction and dissatisfaction in most survey items at baseline. Both home and clinic BP rates showed a significant decrease after switching to the ARB/CCB combination tablet. Patient satisfaction increased for the following survey items: treatment, 69.4% (59/85) to 90.1% (73/81); antihypertensive drugs, 60.0% (51/85) to 76.5% (62/81); clinic BP, 37.0% (31/84) to 68.8% (55/80); and home BP, 41.2% (35/85) to 67.5% (54/80). Component ratios of both patient and physician satisfaction showed significant increases in the following survey items: satisfaction with treatment, 18.8% (16/85) to 65.4% (53/81); involvement in treatment, 44.7% (38/85) to 65.4% (53/81); antihypertensive drugs, 18.8% (16/85) to 55.6% (45/81); clinic BP, 10.7% (9/84) to 46.3% (37/80); and home BP, 9.5% (8/84) to 46.3% (37/80). Our results indicate that, together with the effectiveness of the ARC/CCB combination tablet, participation in a satisfaction survey and access to a home BP monitor may have contributed to an increase in patient involvement in their treatment, a more mutual relationship between patients and physicians, and improvement in patient satisfaction. Conclusion: After switching to a ARB/CCB combination tablet treatment, better control of BP was found in patients with insufficient hypotensive effect from ARB or CCB monotherapy. Surveys showed that satisfaction rate for patients and physicians were improved in addition to patient-physician concordance.

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