Abstract P330: Assessment Of The Prevalence Of Arterial Hypertension Depending On Environmental Living Conditions

Abstract

Materials and methods: A one-stage population-based epidemiological study of a random sample of 3446 people stratified by age and sex from an unorganized population of Rostov-on-Don was performed. In order to determine the association of hypertension and environmental comfort, all the subjects, depending on the environmental comfort of living, were divided into 2 groups, which were formed on the basis of the "Map of environmental comfort of living in the city of Rostov-on-Don", developed by V.V. Privalenko. The total environmental pollution was determined by the dust load, the content of heavy metals and other toxicants in atmospheric deposition, the degree of soil pollution with heavy metals and oil products, the level of occurrence (flooding) and the scale of groundwater pollution, and the noise level. The 1st group included residents living in regions with low to moderate pollution levels; in the 2nd group - with strong and very strong pollution. The duration of residence of respondents in an area with a certain environmental comfort of living was at least 5 years. Statistical processing of the data was carried out using the program Statistica 6.0. Results: When analyzing the frequency of prevalence of AH depending on the environmental comfort of the area of residence, it was found that in people living in environmentally comfortable areas, AH was detected in 639 people (42.86%). At the same time, among the population of Rostov-on-Don living in ecologically uncomfortable areas, hypertension was registered in 396 people (49.26%), which is significantly higher than the prevalence of hypertension in group I (p = 0.003). Analysis of associations of hypertension in the population of Rostov-on-Don and the environmental comfort of the area of residence revealed that in the group of people who lived in ecologically uncomfortable areas, the prevalence of hypertension was significantly higher than in the group of people with environmentally comfortable living conditions: odds ratio = 1.30 (95% confidence interval 1.09-1.54; p = 0.003). When analyzing the average levels of blood pressure depending on the area of residence, it was found that the level of SBP in people living in areas with environmentally uncomfortable conditions is significantly higher (p <0.001) than in people living in environmentally comfortable areas: for men - 140.91 ± 0.8 mmHg and 136.0 ± 0.4 mm Hg, and in women - 133.42 ± 0.5 mm Hg. and 128.2 ± 0.6 mm Hg, respectively. Findings: The prevalence of hypertension among Rostov-on-Don residents living in environmentally uncomfortable areas is significantly higher (p<0.001) than in environmentally comfortable areas (49.26% and 42.86%, respectively).