Abstract P312: Lack of Association Between Habitual Sleep Duration and Obesity Measures in Adolescents with Adequate Sleep

Abstract

Introduction: In general, 7-8 hours/night of sleep is considered as adequate amount of sleep. Although subjectively reported sleep duration has been associated with obesity, the relationship between objectively-measured sleep duration and obesity has been reported inconsistently. Hypothesis: We assessed the hypothesis that there is lack of association between objectively-measured sleep duration and obesity measures in adolescents who generally sleep adequately. Methods: We used data from 421 adolescents in the Penn State Child Cohort follow-up examination. Polysomnography (PSG) was used to objectively measure the sleep duration for one night. Actigraphy was used for 7 consecutive nights to objectively measure and calculate each participant’s habitual mean sleep duration. Anthropometric measurements, including waist circumference, weight, and height, were collected from each participant. Age and sex-specific BMI percentile was calculated. The participants also underwent a dual-energy x-ray absorptiometry scan to assess abdominal obesity, as measured by Android/Gynoid (A/G) fat ratio, Android/whole body (A/W) fat proportion, visceral fat area, and subcutaneous fat area. Multivariable adjusted linear regression was used to analyze the association between sleep duration and obesity measures. Results: The means (SD) of the PSG and actigraphy-measured sleep duration were 7.4 (0.9) and 7.0 (0.8) hours, respectively. As shown in the table, objectively-measured sleep duration was not significantly associated with BMI percentile, after controlling for age, race, sex, and AHI. After further adjustment for BMI percentile, none of the regression coefficients between sleep duration and abdominal obesity measures reached statistical significance. Conclusions: In adolescents with generally adequate amount of sleep, there is lack of association between habitual sleep duration and obesity measures. The findings should not be generalized to adolescents whose sleep duration is outside the range of our data.