Abstract P294: Short-Term Outcome of Post-Stroke Fatigue During the Transition From Hospital to Home

Abstract

Background and Purpose: Post-stroke fatigue (PSF) is a frequent complication that worsens the patient’s rehabilitation outcomes and quality of life. Many studies have demonstrated a robust relationship between PSF and post-stroke depression and insomnia. However, sarcopenia was usually not taken into account. As stroke survivors manage and adapt to their functional limitations, the rhythms, and routines of life poststroke changes. At 1 month after discharge home, frustration is a common response to these changes. Therefore, this study was aimed to investigate the impact of post-stroke fatigue from the acute phase to the first month after discharge and assess the possible contributions of sarcopenia to discharged PSF. Design: A single-center prospective observational study. Participants: 94 patients with acute stroke were recruited between May 2019 and July 2020. Methods: Clinical and stroke characteristics were collected from electronic medical records. Pre and post-stroke factors were collected by questionnaire. The main outcomes were included fatigue, depression, insomnia, sarcopenia, and health-related quality of life (QOL) was assessed at admission, and one month after discharged home. Fatigue was measured using the Fatigue Assessment Scale. Sarcopenia was measured using the SARC-F questionnaire. Results: The prevalence of PSF was 25.5% at admission and 29.8% at one month after discharged home. PSF at admission was associated with fatigue (p<0.01), insomnia (p<0.01), higher SARC-F scores (p=0.026), and lower QOL scores [Physical Component Score (p=0.029) and Mental Component Score (p=0.006)] at one month after discharged home. Conclusions: There is a really beginning that transition for stroke patients at discharge from hospital to home. In this study, PSF during hospitalization can affect sleep status and QOL after discharge, and which is consistent with previous studies. It is worth noting that patients with PSF at admission had higher SARC-F scores after discharged home. Muscle wasting is a common complication accompanying stroke, which may not only contribute to physical function reduction but also psychological function, it deserves more attention in clinical practice and scientific research.