Abstract P270: Increase of Total Peripheral Vascular Resistance and Arterial Stiffness in Non-Diabetic Hypertensive Patients With Overweight, Compared With Hypertensive Patients of the Same Age With Normal Body Mass Index

Abstract

Introduction: it is known that obese hypertensive patients (HTAO) have more difficulties for the better control of blood pressure, being involved many factors that try to explain this situation. However, little has been said regarding total vascular resistance and arterial stiffness (AS) in overweight patients (OWHTA), so we present this work that could provide data of interest in these Objectives: to assess the relationship between adequate control of blood pressure, AS and TPR in patients with OWHTA compared with hypertensive patients with a normal body mass index (BMI). Material and Method: cross-sectional and prospective study of a cohort of 1700 male patients (P) with hypertension, we have 290 P divided into two groups: OWHTA Group 190 P with BMI between 25 and 29 (65 ± 8 years) and Group HTA: 100 P with BMI <25 (66 ± 6 years) who have received treatment from their GP, to keep the BP below 140/80 and apparently were well controlled. A 24 hours blood pressure holter (ABPM) was performed in all patients, and augmentation index (AI) ,pulse wave velocity (PWV) as well as the TPR were measured. The results were compared in both groups and are presented in the following table: Results: Table of results: *means p value less than 0.05. Conclusions: according to our data, in hypertensive males with overweight there are already aggravating factors such as the difficulty for better hypertension control , increase in AS and a significant increase in the TPR that has been seen in obese patients. All of these factors make the cardiovascular risk of these patients much greater, and forces the physician to be more demanding with the therapeutic measures.