Abstract P-260: ASSESSMENT OF PEDIATRIC LOGISTIC ORGAN DYSFUNCTION (PELOD) SCORE AND IMPACT ON MORTALITY OF PEDIATRIC ICU PATIENTS IN A TERTIARY GOVERNMENT HOSPITAL: PROSPECTIVE OBSERVATIONAL COHORT STUDY

Abstract

Aims & Objectives: To analyze the prognostic value of Pediatric Logistic Organ Dysfunction (PELOD) score in the presence of organ dysfunction. Methods A prospective observational cohort study was conducted in the Pediatric Intensive Care Unit (PICU) of a tertiary government hospital in the Philippines from July 15, 2016 to July 14, 2017 including term newborn to <19 years of age. Eighty three subjects were enrolled. PELOD Score was calculated in the first 24 hours of admission. Outcome measures as survival or non-survival at the end of hospital stay was recorded. Results Of the 83 patients included, 51 (61%) were male and 32 (39%) were female; with a mean age of 5 years old and median length of stay of 5 days. Mortality rate was 43.4%. PELOD Scores of non-survivors 25.4 (22.4) was significantly higher (p<0.001) than survivors at 4.9 (5.9). Fifty five percent had Multiple Organ Dysfunctions Syndrome (MODS) upon admission with 100% mortality rate for organ dysfunction of ≥ 4. ROC curve analysis for predicting death was 0.827 (95% CI, 0.733–0.920, P <0.001) indicating a very good discriminatory ability. PELOD score of 15 correlated with 50% probability of death and Risk Ratio analysis (Chi square = 25.395 P < 0.001) reveals the risk of dying of patients with PELOD score >15 is 3.3x that of with score ≤15.Conclusions PELOD score is a reliable prognostic predictor of mortality. Cardiovascular and neurologic dysfunctions were highly associated with mortality. Increasing number of organ dysfunction was correlated with increasing PELOD scores and mortality rate.