Abstract P224: Effect Of Body Mass Index On In-hospital Outcomes In Patients Undergoing Transcatheter Aortic Valve Replacement

Abstract

Introduction: The prevalence of obesity in the US is 41.1% and is on the rise. Data are limited and results are mixed on the effect of body mass index (BMI) on outcomes of transcatheter aortic valve replacement (TAVR). The objective of this study was to determine the effect of BMI on the in-hospital outcomes of patients undergoing TAVR. Methods: Data from the 2015 and 2016 Health Cost and Utilization Project Nationwide Inpatient Sample database was used. Patients who underwent TAVR were identified and in-hospital outcomes compared between patients with a normal BMI and underweight, overweight, obese, and severely obese patients. Propensity score matching was done using a greedy matching algorithm. Results: A total of 2,618 patients were included in this study. The rate of in-hospital mortality was highest in underweight patients (2.94%) and lowest in overweight (0.49%) patients. It was 2.13% in normal weight, 1.23% in obese and 1.97% in severely obese patients. There was no statistically significant difference in in-hospital mortality between overweight and underweight (0.49% vs. 2.94% p=0.056) overweight and normal BMI (0.49% vs. 2.13% p=0.16), overweight and obese (0.49% vs. 1.23% p=0.35) and overweight and severely obese (0.49% vs. 1.97% p=0.14). Compared with overweight patients, underweight (5.6 vs. 7.0 days p=0.07 ) and normal patients (5.6 vs. 7.5 days p=0.03) had the highest mean length of hospital stay (LOS). There was no significant difference in the proportion of patients discharged home among all BMI categories (p=0.23). Conclusions: There was no significant difference among the BMI categories for in-hospital mortality and the proportion of patients discharged home. Overweight patients had a shorter LOS compared with underweight and normal BMI patients.