Abstract P2122: Coronary Heart Disease And Arthritis - An Analysis Of 2 Year Behavioral Risk Factor Surveillance System (BRFSS) Data

Abstract

Introduction: Arthritis has increased systematic repercussions either by extra-articular manifestations or due to limited activities. Studies have fined an association between arthritis and heart disease. In this study, we try to find that arthritis is an independent association for myocardial infarction (MI) or coronary heart disease (CHD). Methods: In this study, we used the 2020 and 2021 Behavioral Risk Factor Surveillance System (BRFSS), a large, nationally representative, cross-sectional telephone survey. The data was divided into the participants having arthritis or no arthritis. Results were pooled and were represented with an odds ratio (OR) with a 95% CI interval. We used a logistic regression model to pool the results and adjusted for different variables. Two different models were constructed, and ANOVA was used to compare different models. The analysis was done by using R statistical software. Fisher t-test was used to compare between 2 groups. P-value < 0.05 was considered significant. Results: Pooled results of the BRFSS survey led to 835,452 participants included in the final analysis. Of the included participant, 267020 has arthritis, and 568432 does not. 38.7% were males, and 61.3% were females. In the arthritis group, 38.7% were males, and 61.3% were females. Also, 55.1% of individuals in the arthritis group are older than 65. Our analysis found that arthritis people have a higher prevalence of diabetes and stroke. We analyzed logistic regression after adjusting for sex, race, age, diabetes, stroke, and BMI. It was found that participants with arthritis have higher odds of MI or CHD ( OR = 1.055, 95% CI 1.154-1.157, p-value < 0.001) compared to non-arthritis people and when adjusted for sex, race, age it was 1.074, 95% CI 1.073-1.075, p-value<0.001). Conclusion: We find that arthritis is associated with an increased risk of MI or CHD independent of other risk factors. Hence, patients with arthritis need close monitoring for heart-related disease.