Abstract P115: The Epidemiological Profile Of CKD Among African American Men And Women: Findings From The Jackson Heart Study

Abstract

The prevalence of CKD is paramount. CKD affects almost 1 in 7 adults in the United States and is associated with increased rates of cardiovascular disease. While African Americans make up about 13 percent of the population, they account for 35 percent of the people with kidney failure in the United States. The prevalence of early CKD is equivalent across racial and ethnic groups in the United States, but CKD progresses to end-stage renal disease far more rapidly in minority populations, with rates nearly four times higher in African Americans than in whites. The purpose of this study is to address the emergence of chronic disease complications in the African American community that focuses on associations with prevalent CKD outcomes in the JHS. Epidemiological study design used to access the preliminary data to derive conclusions about CKD. CKD was assessed by the JHS participants, who self-reported their CKD status/history. CKD was measured using the Renal form and History of CKD form that was given as a questionnaire within the JHS during Examination 1 Period. CKD was measured by Jackson Heart Study’s estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2 to determine CKD status. African Americans have a disproportionate burden of CKD, which tends to have an earlier onset and a more rapid progression in this population. From a population health standpoint, CKD factors such as smoking, diabetes, history of hypertension, dietary patterns, physical activity, blood apolipoproteins and psychosocial factors account for more than 90% of the population-attributable risk. African American men and women with CKD is viewed among the highest-risk groups for cardiovascular events and disease. Race and ethnicity are associated with sociocultural and biologic variations that influence the risk and progression of CKD. Understanding these factors for minority populations can help in targeting interventions to decrease the disproportionately high rates of CKD progression and complications. As prevalence of chronic disease increased, public health’s focus on health- related behaviors and risk factors shifted the discipline’s attention to considering the neighborhood's influence on social determinants of health.