Abstract

Background: In recent years, there has been an increasing interest in the association between neighbourhood environments and cardiovascular disease (CVD) outcomes. Applying advanced linkage techniques to existing databases enables new and more in-depth research in this field. Aim: To investigate the association between fast food restaurant (FFR) density and incident CVD. Methods: Through linkage with the Dutch Population Register, Hospital Discharge Register and Cause of Death Register we obtained a cohort of 35+ years adults who at 01-01-2009 had lived at the same address for 15 years and were not previously admitted for CVD during this period. We followed these persons for one year for incident CVD. Trough linkage with the Locatus database, a nationwide retail database, we obtained information about the number of FFR’s within 500m, 1000m and 3000m buffers from the exact address. Logistic regression analyses was used to investigate the association between FFR density and CVD incidence. We adjusted for age, gender, marital status, country of origin, area-level SES , comorbidity, and degree of urbanisation. Results: In total 3,146,469 adults (46% male), aged 59.2 ± 12 were included. After one year 72,811 (2.3%) persons suffered from an incident CVD. The association with the number of FFR and incident CVD in both 500m, 1000m and 3000m buffers were shown in table 1. Conclusion: There is a modest association between FFR and incident CVD. The association was stronger when FFR’s are within 500m from a person’s home address and when there is a high number of FFR’s. Table 1: The association (OR (95% confidence interval)) with the number of FFR and incident CVD in both 500m, 1000m and 3000m buffers. Adjusted for age, gender, marital status, country of origin, area-level SES , comorbidity, and degree of urbanisation.

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