Abstract P060: Chronic Gout And Hypertension: A Nationwide Analysis Of Patient Demographics

Abstract

Introduction: Hypertension (HTN) contributes significantly to cardiovascular disease (CVD) and chronic gout (CG) is associated with HTN. Our aim is to characterize patient demographics of patients with HTN and CG. Methods: This was a retrospective cohort study using the National Inpatient Sample, Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality to identify admissions in adults with principal and secondary diagnoses of HTN and CG in 2019. Multivariate linear and logistic regression models were adjusted for age, gender, race, household income, insurance status, Elixhauser comorbidity score, hospital location, and bed size. Primary outcome was all-cause mortality, and secondary outcomes were length of stay (LOS) and total charge in USD. Results: Out of 9,582,450 hospital admissions with HTN, 17,710 had a diagnosis of CG. Mean age of 67.5 ± 0.23 years in the CG-HTN group compared to 65.74 ± 0.06 years (p<0.001). Compared to the non-CG-HTN group, there were more males in the CG-HTN group (75% vs 48%, p<0.001). CG-HTN was more common in Asian and Pacific Islanders. Alcohol abuse, arthropathies, leukemia, dementia, peripheral vascular disease, obesity, and complicated diabetes was associated with the CG-HTN group. Compared to non-CG-HTN, CG-HTN cohort had lower all-cause mortality rate (1.13% vs 1.69%, p<0.05), mean LOS of 4.85 vs 4.65 days (0.10 days OR, 95%CI -0.07-0.27, p=0.255), and lower total hospitalization charge -$6,424.47 (95% CI -$9,230.47- -$3,618.47, p<0.001). Conclusion: Chronic gout in the presence of hypertensive disease was associated lower all-cause mortality and hospitalization cost.