Abstract

Introduction: Hypertensive emergency (HE) is a common medical emergency requiring inpatient admission. Our aim was to characterize HE patient demographics and analyze the factors that increases the likelihood for HE readmissions. Methods: This was a retrospective cohort study using the 2019 Nationwide Readmissions Database to identify admissions in adults with a diagnosis HE. Regression models were used. Primary outcome was all-cause 30-day readmission rate, mortality rate, causes and predictors for readmission. Results: Out of a total of 56,648 admissions with HE, 7,753 were readmitted, with a readmission rate of 13.72%. The most common causes for readmissions were CHF exacerbation in setting of CKD stage 1-5 11.51% (892 of 7753), hypertensive emergency 11.48% (890 of 7753), hypertensive urgency 7.92% (614 of 7753), AKI 4.67% (362 of 7753), Sepsis 3.12% (241 of 7753), NSTEMI 2.44% (189 of 7753), and ischemic CVA 1.79% (139 of 7753). Compared to index admissions, readmissions had higher mortality rate (1.39% vs 0.35%), LOS (5.13 days vs 3.65 days), and total charge ($58,172.50 vs $42,273.43). See table 1 for index admission group demographics. The top predictors for readmissions were, reported in odds ratio, ESRD 3.43, hypertension 2.30, discharged AMA 2.29, diabetes mellitus 1.92, transfer to nursing facility 1.5, drug abuse 1.40, depression 1.28. Conclusion: HE has a high readmission rate of 13.72% with the most common cause for readmission being CHF exacerbation, followed by recurrence of HE, AKI, sepsis, NSTEMI, and ischemic CVA. The best predictor for HE readmission was ESRD, followed by hypertension, discharged AMA, and diabetes mellitus.

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