Abstract
Aims & Objectives: It is difficult to make a precise diagnosis among patients with febrile status epilepticus on admission to identify the cases of acute encephalopathy with sequelae. However, it is necessary to make an early diagnosis of cases with sequelae, in order to determine whether an aggressive treatment is required to alleviate the possibility of sequelae. Thus, we evaluated the clinical characteristics of the patients with febrile status epilepticus on admission. Methods We reviewed the medical charts of the patients admitted to our PICU from March in 2016 to December in 2017. We found 14 cases with febrile status epilepticus. Of which 4 developed sequelae. We evaluated the differences between the patients grouped with and without sequelae for the following data. 1.aEEG on admission 2.Regional SrO2 of both brain frontal lobe and liver on admission 3.Serum liver function and coagulation function Results All patients with sequelae and 2 cases without sequelae had high-amplitude slow waves on aEEG. All patients with sequelae and 1 case without sequelae showed that regional SrO2 of both frontal lobes were more than 10% higher than that of the liver. All patients with sequelae and 1 case without sequelae showed liver dysfunction with coagulopathy. Conclusions Based on this study, the combination of aEEG, regional SrO2 and liver dysfunction with coagulopathy could be useful to make an early diagnosis to identify the cases with sequelae. However, a larger number of patients should be included to clarify the results of this study.
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