Abstract
Aims & Objectives: Microalbuminuria is an earlier sign of vascular damage. Hovewer it is accepted as an increased risk for cardiovascular morbidity and mortality especially in high risk populations such as diabetics and hypertensives. We aimed to evaluate the prognostic value of microalbuminuria in children admitted to the pediatric intensive care unit (PICU). Methods In this prospective study we measured the microalbumin levels of patients admitted to the our 12 bed pediatric intensive care unit in an university hospital between December 2014 and November 2015. 250 patients included who were 1 month to 18 years old, monitored at least 24 hours in PICU and meeting study criteria. PRISM III and PELOD scores were calculated for all patients. The collected data was analyzed with statistical methods and compared with mortality scoring systems and observed mortality. Results Microalbuminuria values were significantly higher in non-survivors (48 mg/g) than the average of survivors (18 mg/g) (p<0,05). At a cut off value of 32 mg/g, albumin-creatinine ratio measured at admission may be able to discriminate between patients a with sensitivity of 85%, and specificity of 70% (p<0,01). Conclusions Microalbuminuria may be used as a simple and useful to predict mortality in PICU. Additionally microalbuminuria may be involved in the pediatric mortality scoring systems in the future.
Published Version
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