Abstract P-118: THE APPLICATION OF CONTINUOUS BLOOD PURIFICATION IN PEDIATRIC INTENSIVE CARE: AN ELEVEN-YEARS EXPERIENCE

Abstract

Aims & Objectives: To report the efficacy and outcomes of Continuous Blood Purification (CBP) in our PICU over the past eleven years Methods Clinical data of the children treated with CBP in the PICU of Children’s Hospital of Fudan University from Jan. 2004 to Dec. 2014 was retrospectively analyzed Results A total of 359 patients were admitted into our PICU and underwent blood purification treatment during this period. The primary diseases were sepsis, followed by renal failure, liver failure, toxication and autoimmune diseases such as Guillain-Barre syndrome in order. The median PRISM-III score in the first 24 hours after admission is 19 (0–58), and the median ICU days is 8 (1–95) days. In terms of prognosis, a total of 92 children died, the mortality rate was 25.6%. During the eleven years, Sepsis rose to the first place as primary disease, a Hybrid CBP mode by combination of CVVHDF with other blood purification modes was used more often. Several indicates were compared before and after the runs including creatinine Potassium PH and so on, which indicates that CBP treatment is effective Conclusions CBP is safe to use in PICU. In addition, non-renal diseases, especially sepsis has become the main area of its application in PICU