Abstract No.: ABS3618: Implication Of Pre Operative Frailty In Risk Assessment Of Post Operative DeliriumIn Elderly Indian Patients Undergoing Non-Cardiac Surgery

Abstract

Background & Aims:Frailty is defined as result of a progressive decline in homeostatic capacity and is a vicious cycle. Delirium is defined as acute in onset, inattention, with cognition dysfunction and behaviour abnormalitiesMethods:Consenting patients above 65 years of age, undergoing non cardiac surgery were enrolled. Frailty was assessed preoperatively with Modified Fried Criteria (MFC) and patients were divided into Frail (MFC<3/7) and Non frail category (MFC>3/7). Postoperatively patients were assessed for delirium by Confusion assessment method , Montreal Cognitive Assessment and 12 item Mini-Mental State Examination on Day 1, Day 3, and telephonically by T-MOCA at 1 and 3 months postoperativeResults:109 patients were enrolled. Post-operative delirium on Day 1 was seen in 9 (8.25%) patients and all patients belonged to frail category. Cognitive dysfunction assessed by MOCA and MMSE on Day1 was seen in 85.7%(81/98) and 63.3% (62/98) in frail elderly significantly higher than 45.5% (5/11), and 27.3% (3/11) in non-frail elderlies. significantly greater cognitive dysfunction was seen in frail patients at Day3, at one month and at three months (77.6% in frail versus 36.4% in non-frail) too.Conclusion:In our study we found that pre-operative Frail elderly patients had significantly increased post-operative cognitive dysfunction at day 1, 3 and 1st month and 3rd month after non-cardiac surgery. Incidence of postoperative delirium however was similar