Abstract

To compare the results of 40- and 120-minute ethanol sclerotherapies which were performed in a single session for the management of simple renal cysts. We retrospectively reviewed 63 renal cysts in 62 patients treated by single-session percutaneous ethanol sclerotherapy. Thirty-two cysts in 31 patients underwent 40-minute sclerotherapy (group A) and 31 cysts in 31 patients underwent 120-minute retention technique (group B). Under ultrasonographic and fluoroscopic guidance, the cystic fluid was completely aspirated and 50% of the aspirated volume replaced with 99.5% ethanol (maximum, 100 mL). Follow-up of the patients were performed with ultrasonography or computed tomography (CT) at 3 months after sclerotherapy. Overall, technical success rates were 100% in both two groups. Eighteen patients (28.6%) were symptomatic (flank pain or discomfort). Indications of the other patients were large cyst (>5cm; 46%) and increment of the diameter on serial studies (25.4%). There was no significant difference between the two groups in terms of age (62.22 vs. 62.48 years), cyst diameter (8.43 vs. 8.14 cm), volume of aspirated fluid (230.06 vs. 250.16 mL), volume of injected ethanol (77.81 vs. 70.48 mL), and percentage of decrement of cyst diameter (58.6 vs. 53.67%) (P>0.05). After the treatment, flank pain or discomfort resolved in 17 (94.4%) of 18 symptomatic patients. One patient complained persistent flank pain, but no significant abnormality was detected on post-procedural CT images. There were no other complications after therapy in two groups. Single-session ethanol sclerotherapy with 40-minute retention technique is an effective and safe method for the treatment of simple renal cysts. It can reduce the procedural time and length of hospital stay, but there is no statistical difference in therapeutic efficacy between 40- and 120-minute therapies.

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