Abstract No. 471 Procedure times and outcomes of transarterial embolization in rats utilizing augmented reality

Abstract

To evaluate the utility of visualizing pre-procedural imaging in actual 3D space with augmented reality (AR) for transarterial embolization (TAE) of HCC in rats Software by Medivis was used to render DICOM data from T2-weighted rat MRI scans (70 mm x 70 mm FOV, 2 mm slice thickness, 20 slices, 4 averages, 256 x 256 grid size, 256 x 256, TR ∼1.5-2 s, TE ∼60 ms) in actual 3D space prior to TAE from 8/10/2018 to present. 3D volumes were generated using 3D texture mapping and interpolation of the DICOM data. Remote volume rendering using ray casting with optimization techniques was performed on a local workstation equipped with a GTX 1080 GPU and projected wirelessly in real-time via Wi-Fi to Microsoft HoloLens. Volume manipulations including rotation, magnification, and modification of voxel opacities were utilized during HoloLens visualization. Total catheterization times and 3-day survival rates were recorded as well as HoloLens setup and utilization times. Historical comparisons were made to TAEs from 2017 using Welch’s t-test and Fisher’s exact test. Catheterization time was measured from start to end time of fluoroscopy. Results are summarized in Table 1. Reported cases from 2018 included AR utilization prior to TAE. Cases from 2017 served as historical controls without AR utilization. AR utilization demonstrated trends in reducing catheterization time (p=0.18) and improving survival (p=0.24). The proceduralist reported enhanced knowledge and spatial understanding of procedural anatomy in all cases after AR utilization. Utilization of AR for visualizing pre-procedural imaging in actual 3D space may have a beneficial impact on procedure times and outcomes. Although limited, these cases of TAE in rats provide insight on the potential utility of augmented reality for TA(C)E in patients.Table 1Summary of AR Utilization for TAE in Rats*20172018n153Avg total catheterization time (min)42.321.7 (p=0.18)Avg 3-day survival rate53%100% (p=0.24)Avg HoloLens setup time (min)--2.9Avg HoloLens utilization time (min)--3.0*Cases from 2018 included AR utilization prior to TAE. Cases from 2017 were performed without AR utilization. Open table in a new tab