Abstract
Magnetic resonance (MR)-trackable magnetocapsules (MCs) were created to simultaneously immunoprotect pancreatic beta cells and non-invasively monitor, in real-time, portal vein delivery and engraftment using MR imaging (MRI). The purpose of this study was to demonstrate the feasibility of MR-guided, targeted biopsy of MCs containing human islets in order to assess not only their viability and function, but also the host vs. graft tissue response.
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