Abstract
The majority of current animal spinal tumor models are limited in rats, the size of which is too small to be studied for mechanism, efficacy and safety of the newly mini-invasive therapies such as percutaneous vertebroplasty. Although a very few literatures described the spinal tumor models in rabbits, but these models were established by surgical method, which may not be applicable for image-guided percutaneous puncture techniqueS(PPT). In the present study, we used CT-guided PPT to produce a predictable and reproducible spinal tumor model of rabbits and to investigate the onset of the paraplegia and histopathological findings of the animal model.
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