Abstract No. 183 Transjugular intrahepatic portosystemic shunt reduction for medically refractory hepatic encephalopathy

Abstract

Transjugular intrahepatic portosystemic shunt (TIPS) is an established intervention for symptomatic portal hypertension. Following TIPS creation, 25-45% of patients experience hepatic encephalopathy (HE), with symptoms ranging from impaired attention to coma (1). While HE can often be managed medically, refractory cases may require TIPS reduction which can redirect blood flow back through the hepatic parenchyma and decrease the burden of neurotoxic metabolites. The purpose of this study was to evaluate the efficacy of TIPS reduction for the treatment of medically refractory post-TIPS HE.