Abstract
Abstract The presence of bacteria in human solid tumors has been documented for over 100 years. Still, it is only in recent years that a more thorough characterization of this low-biomass microbiome has been pursued. In my lecture, I will describe our efforts to characterize the type of bacteria present across multiple human solid tumors as well as their intratumor location. I will also describe our efforts to study the effect that intratumor bacteria may have on different tumor phenotypes in general and on response to therapy in particular. Citation Format: Ravid Straussman. Characterizing the tumor microbiome and its effects on response to therapy [abstract]. In: Proceedings of the AACR Special Conference on the Microbiome, Viruses, and Cancer; 2020 Feb 21-24; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2020;80(8 Suppl):Abstract nr IA14.
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