Abstract

Abstract Poverty and its associated factors such as education, housing, employment, etc., have tremendous effects on the health of communities and their populations. An extreme form of poverty is the concept of place-based poverty, which is measured through persistent poverty areas where more than 20% of the population has lived in poverty for over 30 years. Persistent poverty areas represent an important subgroup of U.S. counties with higher disease burden and greater cancer mortality where the health consequences of elevated and continuous levels of poverty over time have not been fully investigated. The intersectionality of structural and institutional level factors along with persistent poverty results in increased cancer incidence, delayed cancer diagnosis and treatment, increased morbidity, treatment-related toxicity, and subsequently lower rates of survival. It is important to understand the interrelated effects of persistent poverty and other social, economic, and health factors, including race and ethnicity at the structural and institutional levels to implement interventions to reduce cancer disparities. The NCI seeks to eliminate cancer-related disparities in persistent poverty areas by promoting and conducting health equity research that identifies and addresses the mechanisms contributing to disparities across the cancer control continuum. There are various initiatives are underway focusing on this important research agenda. Citation Format: Amy E. Kennedy. NCI’s persistent poverty research agenda [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr IA044.

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