Abstract

Abstract To date, evidence from modeling studies indicates that precision early detection approaches could potentially improve the benefit-harm balance and the cost-effectiveness of cancer screening programs. A precision program involves risk assessment of all individuals in the population, stratification of the population into several risk groups and tailoring early detection and prevention recommendations to each risk group. Implementing precision program raises number of questions at each stage. It is important not only to generate evidence on the individual ‘jigsaw’ pieces of the program, but also to bring the pieces together in a complex adaptive system, while considering the healthcare organizational readiness for change, the economic and social context. Citation Format: Nora Pashayan. Implementation of population-based precision cancer screening programs. [abstract]. In: Proceedings of the AACR Special Conference: Precision Prevention, Early Detection, and Interception of Cancer; 2022 Nov 17-19; Austin, TX. Philadelphia (PA): AACR; Can Prev Res 2023;16(1 Suppl): Abstract nr IA011.

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