Abstract

Abstract The delivery of radiation for the treatment of cancer is a complicated process that requires both clinical and technical expertise to ensure radiation treatments are safe and effective. Sub-optimal radiation treatments have the potential to result in significant detriment to the patient and several studies have shown radiation treatments, which deviate from established clinical guidelines, result in worse patient outcomes. Therefore, the current radiation treatment process requires substantial multi-disciplinary resources to both generate and verify radiation treatments are of high-quality. In this talk, a previously validated machine learning platform customized for radiation oncology will be presented. The method automatically learns based on data from thousands of previously treated patients which relationships and patterns in radiation oncology image and treatment data and has been applied for automated data mining activities, automated quality assurance to support expedited radiation treatment review, and for radiation dose prediction to develop new radiation treatments by best deciding where dose should be placed and how dose should be delivered without requiring any manual intervention. Therefore, the method can be used to both generate personalized radiation treatments and to quantitatively score radiation treatments for quality and classify radiation treatments that have errors. The automated platform can readily be integrated into current clinical process to improve efficiency in the radiation treatment planning and plan review processes and to better utilize the vast data we have to ensure we are providing patients with highly personalized radiation treatments. Citation Format: Thomas G. Purdie. Automated treatment planning and quality assurance in radiation oncology [abstract]. In: Proceedings of the AACR Virtual Special Conference on Artificial Intelligence, Diagnosis, and Imaging; 2021 Jan 13-14. Philadelphia (PA): AACR; Clin Cancer Res 2021;27(5_Suppl):Abstract nr IA-22.

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