Abstract A126: Human papillomavirus (HPV) vaccination rate by gender identity among US young adults

Abstract

Abstract Background: While national human papillomavirus (HPV) vaccination estimates vary by sex, little is known about variation by gender identity. We sought to estimate HPV vaccination initiation and completion by gender identity among US young adults. Methods: We used 2018-2020 Behavioral Risk Factor Surveillance System data from individuals reporting both gender identity and HPV vaccination status. Weighted, multivariable logistic regression was used to identify factors associated with vaccination initiation and completion. Results: The 6,484 individuals included 3,300 cismales, 3,130 cisfemales, 31 transmales, and 23 transfemales. Vaccination initiation/completion were low, at 40.1% and 17.6%, respectively, and varied by gender identity: cismale=29.1%/9.6%, cisfemale=51.3%/25.8%, transmale=50.1%/5.9%, and transfemale=34.7%/13.0% (P <.0001). In weighted multivariable models, cismales were significantly less likely than cisfemales to initiate (OR:0.39; 95% CI:0.32-0.48) and complete (OR:0.29; 95% CI:0.22-0.37) vaccination, but no significant differences were observed for transmales and transfemales compared to cisfemale. Factors associated with lower initiation included: non-Hispanic Black race (OR: 0.71; 95% CI: 0.54-0.93), high school diploma (OR: 0.57; 95% CI: 0.42-0.78), rural residence (OR: 0.64; 95% CI:0.45-0.90), no insurance (OR: 0.56; 95% CI:0.43-0.74), and no regular provider (OR: 0.67; 95% CI: 0.53-0.84). Factors associated with lower completion included: non-Hispanic Black race (OR: 0.48; 95% CI: 0.34-0.67), Hispanic race (OR: 0.70; 95% CI: 0.49-0.99), married (OR: 0.76; 95% CI: 0.57-0.95), high school diploma (OR: 0.60; 95% CI: 0.42-0.85), and no regular provider (OR: 0.63; 95% CI: 0.46-0.87). Conclusion: HPV vaccination rates in the U.S. are low across all subsamples and future HPV vaccine uptake studies should account for gender identity. Citation Format: Minjee Lee, Wiley D. Jenkins, Bettina Drake, Sarah Van Vickle-Chavez. Human papillomavirus (HPV) vaccination rate by gender identity among US young adults [abstract]. In: Proceedings of the 15th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2022 Sep 16-19; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr A126.