Abstract

Abstract The role of Social Determinants of Health (SDoH)  on adherence to cancer prevention recommendations has not been systematically examined among adults in the United States adults despite  the influential role of SDoH in shaping individuals' health behaviors and outcomes. Our purpose was to  explore the effects of SDoH on adherence to cancer prevention recommendations among  adults in the United States Methods: We used data from the Health Information National Trends Survey (HINTS), 6 cycle (2022).  Adults aged 18 years and above were included. Adherence to cancer prevention recommendations was measured with the 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (WCRF/AICR) Cancer Prevention Recommendations Score.  SDoH was measured based on the American Cancer society's five core SDOH domains (economic stability, social and community context, neighborhood and built environment, education access, and healthcare access). Weighted hierarchical multiple regression models were conducted using each domain of SDOH as a block, controlling for age, gender, race, selfcare efficacy, cormorbidity, cancer risk perception and  belief about cancer,  Jackknife replicate weights were incorporated into the analyses. Results: The sample consisted of 6252 respondents with a mean age of 55.6 (SD, 17.4) years,  The  estimated mean adherence rate  to cancer prevention recommendations among adults in the United States was  40.4% (SD 21.8) .Adherence to  cancer prevention recommendations was positively associated with  having a college education compare to less than high school education (Odd Ratio [OR], 6.29, P = .019),  combined household income of $75,000 and above compare to combined household income of less than $20,000 ( OR, 5.11 , P= .014) , retired compared to full-time employement ( OR, 4.87, P < .001), access to health insurance compared to lack of health insurance  (OR, 4.01, P= .020). These findings suggest that  interventions targeting  the effects of SDoH on cancer on adherence to cancer prevention recommendations may consider the  socioeconomic context of targeted individuals. Such interventions should focus on addressing barriers related to education access, income stability, employment status  and healthcare access.   Citation Format: Adaeze Aroh, Ifeanyi N. Madujibeya. Examining the role of Social Determinants of Health (SDoH) on adherence to cancer prevention recommendations: Evidence from a national representative sample [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr A089.

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