Abstract A035: Examining the health-related quality of life of U.S. Hispanic cancer survivors

Abstract

Abstract Introduction By 2030, Hispanic survivors will likely constitute 20% of the survivor population (4 million people). Compared to non-Hispanic Whites, Hispanic cancer survivors experience worse health-related quality of life (HRQOL) across multiple domains including worse physical, psychological, and social wellbeing. Few studies have examined predictors of HRQOL in a population-based sample of Hispanic cancer survivors. We examined demographic, acculturation, and cancer clinical factors associated with HRQOL in early cancer survivorship. Methodology Utilizing data from the Measuring Your Health (MY-Health) study, which recruited cancer patients from 4 SEER cancer registries between 2010 and 2013, we conducted a secondary analysis of Hispanic survivors who responded to the baseline survey (administered ~9 months after diagnosis; n=908). We examined sample characteristics of the sample, including English language comfort, country of birth, and years in the US. We measured HRQOL outcomes (physical and mental health summary measures, pain interference, anxiety, depression, fatigue, and physical function) using PROMIS® measures validated in English and Spanish. We dichotomized PROMIS scores for clinically relevant symptoms in a cancer population. We conducted linear and logistic regressions examining HRQOL associated with covariates including demographic and cancer characteristics, spirituality, and acculturation factors. Preliminary Results Survivors had a mean age of 60 years, 58% were foreign born, 61% were female, 56% married, 68% had early-stage cancer, 31% had breast cancer, and 23% had prostate cancer. Some survivors reported preferring communicating in English (57%) and those who immigrated to the US had a mean of 30 years in the US. Preliminary results show that this population may be experiencing worse physical and mental health (mean = 43.68 and 47.11; lower scores mean worse health), anxiety, fatigue, and pain (52.7, 53.4, 55.2; high scores mean worse anxiety, fatigue, pain) than national averages (score of 50). Multivariable results are forthcoming. Conclusions In a large and diverse sample of Hispanic cancer survivors, we found survivors report worse quality of life across multiple domains compared to the general population’s self-reported HRQOL. Few interventions have been developed to improve HRQOL for diverse groups of Hispanic cancer survivors. Elucidating factors that affect outcomes can help clarify how to structure interventions to reduce HRQOL disparities in this understudied group of cancer survivors. Citation Format: Manami Bhattacharya, Kristi D. Graves, Roxanne Jensen. Examining the health-related quality of life of U.S. Hispanic cancer survivors [abstract]. In: Proceedings of the 15th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2022 Sep 16-19; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr A035.