Abstract A013: Uptake and predictors of Covid-19 vaccination among United States’ cancer populations

Abstract

Abstract The COVID-19 pandemic led different stakeholders to call for measures to reduce the morbidity and mortality associated with it. However, following the development of a vaccine, United States adults were reluctant to get vaccinated against COVID-19. Our objective was to evaluate the uptake of COVID-19 vaccination among at risk adults with cancer, and to analyze the predictors of vaccination. Using 2021 data from the National Health Interview Survey, COVID-19 vaccination uptake among 2703 respondents representing 150 million United States adults with any type of cancer was explored, as well as the sociodemographic and comorbid predictors of the vaccination. Chi-square analysis was used to analyze differences between the vaccinated and unvaccinated respondents, and a multiple logistic regression analysis was used to determine the predictors of COVID-19 vaccination. Among 2703 respondents with any type of cancer, 2317 (83.8%) of them reported vaccination against COVID-19. As compared to those who were unvaccinated, those who were vaccinated were mostly 65+ years and above (88.7% vs 11.4%), females (81.9% vs 18.1%), whites (84.0% vs 16.0%), insured (84.7% vs 15.3%), and educated (92.0% vs 8.0%). With regards to the sociodemographic and comorbid predictors of COVID-19 vaccination. As compared to those less than 40 years of age, those between 40-64 years (AOR 2.55, CI 1.45 – 4.48; p=0.001) and 65 years and above (AOR 4.82, CI 2.65 – 8.79; p=<.001) were more likely to be vaccinated, the insured were more likely be vaccinated as compared to the uninsured (AOR 2.85, CI 1.42 – 5.71; p=0.003), and those who were educated were more likely to be vaccinated (AOR 3.10, CI 2.22 - 4.32; p=<.001) as compared to those who were uneducated. However, being a current smoker of cigarettes was associated with reduced odds of being vaccinated against COVID-19 infection compared to non-smokers (AOR 0.67, 0.47 – 0.97; p=0.035) While there appears to be a reasonable uptake of the COVID-19 vaccine among US adults with any type of cancer, efforts are needed to increase vaccine uptake among those who smoke cigarettes. In addition, younger, uninsured, and less educated adults with any type of cancer may be at a higher risk of contracting COVID-19 infection, and therefore measures to increase uptake in these groups are also. Citation Format: Tayla Greene, Kikelomo Olaosebikan, Osahon Idolor, James Appiah-Pippim. Uptake and predictors of Covid-19 vaccination among United States’ cancer populations [abstract]. In: Proceedings of the AACR Special Conference in Cancer Research: Pancreatic Cancer; 2023 Sep 27-30; Boston, Massachusetts. Philadelphia (PA): AACR; Cancer Res 2024;84(2 Suppl):Abstract nr A013.