Abstract 9883: Outcomes of Cardiac Arrest Hospitalizations in Obese Patients with vs. without Prior Bariatric Surgery Status: A Nationwide Propensity-Score Matched Analysis

Abstract

Introduction: Prior bariatric surgery (PBS) in obese patients curtail the risk of future cardiovascular diseases, but its role in outcomes of obese patients developing new acute cardiac events remains largely unknown. We assessed the outcomes of cardiac arrest (CA) by the effect of bariatric surgery on obese patients. Methods: Hospitalizations among adult obese patients with CA were identified using the National Inpatient Sample (2015October-2017). Propensity-matched analysis (1:1) was performed for sociodemographic/hospital characteristics to identify two cohorts, with (PBS+) or without (PBS-) status. The primary endpoint was in-hospital mortality and the secondary endpoint was healthcare resource utilization. Results: Propensity matched obese cohorts admitted for CA, PBS+ vs PBS- (n=1275 each), had patients with comparable age (mean 58 years), with a higher frequency of white (>70%), females (>60%), and Medicare enrollees (>40%). PBS+ cohort had lower rates of diabetes (27.8% vs 36.1%), hyperlipidemia (33.7% vs 48.6%), renal failure (17.3% vs 22.0%), chronic pulmonary disease (11.8% vs 21.2%) and higher rates of anemias (18.4% vs 12.2%), liver disease (5.1% vs 2.4%) and alcohol abuse (6.7% vs 2.4%) vs. PBS- cohort (p<0.05). Despite a lower burden of cardiovascular disease (CVD) risk factors in the PBS+ group, there was no significant difference in all-cause mortality (46.3% vs 45.1%, p=0.551) between the two cohorts (Table 1) . The PBS+ cohort was less often transferred routinely and had a shorter hospital stay with equivalent hospital charges compared to the PBS- cohort (p<0.001). Conclusions: This propensity-matched analysis showed that the prior bariatric surgery status (irrespective of timeframe) did not improve the survival in CA admissions among obese patients. Preventive strides are warranted to control persistent CVD risk factors that could hinder the benefits of surgery in obese patients and worsen outcomes of future cardiac events.