Abstract
Background: Transcatheter aortic valve replacement (TAVR) is increasingly utilized in the treatment of aortic valve disease. We assess echocardiographic changes over time to evaluate cardiac remodeling following TAVR between Veteran (VA) and non-VA populations. Methods: Retrospective analysis of 121, single operator TAVR procedures completed between March 2018 and June 2020 at the University of Illinois Hospital in Chicago, IL. Patients included those referred from the affiliated Jessie Brown Veteran Affairs hospital with the following inclusion criteria: transthoracic echocardiogram (TTE) at baseline and 6-month follow-up. Chi-Square tests were used to analyze categorical variables, paired t-tests for continuous variables, and multivariate analysis for subgroups. Results: One hundred and fifteen patients (VA: 59, non-VA: 56) were included in this study. The population had a mean age of 77.0 vs 73.2, BMI of 28.2 vs 30.4, 96.6% vs 56.6% male (p<0.001), and 57.6% vs 33.9% White (p=0.011) between VA and non-VA patients respectively. Overall, there was no significant difference in chamber dimensions, LVEF, and RVSP; however, there was a significant decrease in wall thickness. Multivariate subgroup analysis showed no significant difference between groups except for RVSP. Conclusion: Overall, our study shows positive cardiac remodeling post TAVR, but there is no significant difference when comparing VA to non-VA populations. Although additional studies with larger sample sizes are warranted, the lack of disparity between these subgroups is reassuring.
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