Abstract 9037: Effectiveness of Online CME at Improving Cardiologists’ and Pcps’ Knowledge and Confidence Related to Diagnosis and Treatment of Hereditary Transthyretin Amyloidosis

Abstract

Introduction: Despite advances in hATTR management, patients experience delays in diagnosis and initiation of targeted treatment, resulting in suboptimal care. We sought to determine if online continuing medical education (CME) could improve the knowledge and confidence of cardiologists and primary care physicians (PCPs) related to diagnostic features of hATTR and targeted treatment strategies for hATTR. Methods: This CME intervention comprised of a 30-minute online video-based discussion between 2 expert faculty. Responses to 3 multiple-choice, knowledge questions and 1 self-efficacy, 5-point Likert scale confidence question were analyzed using a repeated pairs pre-/post-assessment study design. A chi-square test (P <.05 is considered significant) assessed pre- to post-activity change. The activity launched March 26, 2020 and data were collected through June 10, 2020. Results: In total, 144 cardiologists and 384 PCPs were included in the study. Overall, there were knowledge and confidence improvements seen among all groups from pre- to post-assessment: • 8% of cardiologists (P=ns) and 16% of PCPs (P<.0001) improved at identifying diagnostic features of hATTR • 23% of cardiologists (p<.001) and 27% of PCPs (p<.001) improved at selecting MOA of current treatment approaches targeting TTR in patients with hATTR • 40% of cardiologists and 56% of PCPs had a measurable increase in confidence in recognizing early diagnostic features in patients with hATTR Continued educational gaps: • 12% of cardiologists and 14% of PCPs failed to select diagnostic features of hATTR • 59% of cardiologists and 58% of PCPs failed to select MOA of current treatment approaches targeting TTR in patients with hATTR Conclusions: This study demonstrates the success of online CME on improving knowledge and confidence of cardiologists and PCPs related to recognition of diagnostic features in patients with hATTR. Continued gaps were identified for future educational targets.