Abstract
Abstract Background: Invasive pulmonary adenocarcinoma is composed of five histologic patterns including lepidic, papillary, acinar, solid, and micropapillary patterns by the International Association for the Study of Lung Cancer, the American Thoracic Society, and the European Respiratory Society classification. Many researches for histologic pattern and survival rates were performed, but confirmative relationships of histologic pattern and patient's prognosis are unclear. Methods: We searched PubMed using the keywords “IASLC/ATS/ERS classification” and “International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society”. Review articles and case reports were excluded, and duplicated data, insufficient data, and overlapping articles are also excluded. The pooled analysis was performed with the Comprehensive Meta-analysis Software version 2.0. Results: Lepidic predominant pattern had significantly lower recurrence and expire than acinar, papillary, solid or micropapillary pattern. Acinar or papillary pattern had significantly lower recurrence and expire than solid or micropapillary pattern. Conclusions: Invasive adenocarcinoma with lepidic predominant pattern has better prognosis than that with the other predominant patterns. Acinar and papillary predominant patterns have better prognosis than solid and micropapillary predominant patterns in invasive pulmonary adenocarcinoma. There are no different prognoses between acinar and papillary predominant patterns, and solid and micropapillary predominant patterns of invasive pulmonary adenocarcinoma. Citation Format: Keon Uk Park, Jin Young Kim, Hun Mo Ryoo, Ilseon Hwang. Correlation of prognosis and histologic patterns by the IASLC/ATS/ERS classification in invasive pulmonary adenocarcinoma: A meta-analysis. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 856. doi:10.1158/1538-7445.AM2015-856
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
