Abstract
Abstract Objectives This study systematically reviews the literature on the effect of home-based supportive care (HbSC) programs on the quality of life (QoL) of patients with advanced cancer. Methods: The research question ‘Do home-based supportive care programs for patients with advanced cancer improve their QoL?’ was addressed. After registering the plan with PROSPERO (CRD42021235007), literature published from 1 January 1990 to 11 July 2022 was searched on Ovid Medline, Embase, Cochrane library, Web of Science, and Google Scholar and reviewed for inclusion based on predefined criteria. This review only included trial studies published in English. Results: Of 5288 articles identified, 17 studies were judged suitable for inclusion in this review. The components of HbSC programs included home visits, patient and caregiver education, home nursing, psychotherapy, exercise, and telephone consultation. Eight programs included conducting multidisciplinary team meetings. Improvements in QoL were reported in six studies. Specific areas of QoL improved when interventions included home nursing, psychotherapy, patient and caregiver education, and exercise. Conclusion: HbSC programs appear to enable the improvement of the QoL of patients with advanced cancer. The area of QoL that shows improvement could vary depending on the HbSC components. More studies that address HbSC programs are needed to select patients at the proper time and provide suitable programs for patients to benefit most. Citation Format: Inyoung Hwang, Go-Un Wo, Sun-Young Lee, Shin Hye Yoo, Kyae Hyung Kim, Min-Sun Kim, Jeongmi Shin, Hyejin Jeong, Min Seol Jang, Sun Kyung Baek, Eun Hee Jung, Dong-Wook Lee, Belong Cho, Jin Ho Park, Hyuktae Kwon. Home-based supportive care programs for quality-of-life outcomes among patients with advanced cancer: A systematic review [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 6302.
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