ABSTRACT 544

Abstract

Background and aims: Children with severe cardio-respiratory failure run a higher mortality. Aims: To analyze the effects of ECMO (extracorporeal membrane oxygenation) treatment to children with severe cardio-respiratory failure in PICU. Methods: 15 children cases (non-cardiac surgical diseases) with ECMO (BIO-CONSOLE®560; BIO-PUMP®BP50) treatment during 2011.12~2013.11 were analyzed retrospectively. All cases fail to response to conventional therapy including mechanical ventilation before ECMO, and with no irreversible fatal underling disorders. Results: Etiology of 15 cases included: 8 cases with severe pneumonia, 5 cases with cardiac compromise, 2 cases with septic shock. Patients’ ages varied from 1 month to 11 years (average 2 years old). All patients were given VA ECMO through right carotid artery and internal jugular vein cannulation. ECMO blood flow were kept in 70~100 ml/kg/min, gas flow in 1~4 l/min to maintain good oxygen delivery, and heparin infusion to keep ACT in 180~220 sec. The ECMO running time varied from 15 hours ~ 11days (average 125 hours). 7 cases were added CRRT treatment due to oliguria. After ECMO treatment, 10 cases (66%) were successfully weaned from ECMO and finally be discharged from hospital. The main ECMO complications we have met in ECMO include mechanical failure, oxygenator leakage, bleeding or thrombosis.Table 1: Outcome of children with ECMOConclusions: ECMO is a useful life support method in PICU for severe cardio-respiratory failure who fails to response to all treatment. Above half of the patients could be rescued by ECMO.