Abstract

Back ground: Treatment of acute ST segment myocardial infarction (STEMI) has improved over the last 2 decades. The goal of this study was to determine trends in the mortality of patients with acute STEMI in the United States over the years based on gender and race. Method: The Nationwide Inpatient Sample (NIS) database was used to analyze the age adjusted mortality rates for STEMI from 1988 to 2004 for inpatients above the age of 40. ICD-9-CM codes consistent with acute STEMI were utilized. Results : A total of 163,915 hospital deaths occurred during the study period. From 1988 the age-adjusted mortality rate declined regardless of gender or race. However, women and African Americans had higher rate of acute STEMI related mortality in comparison to men and Caucasians over the years studied (For 1988 age adjusted mortality rate from STEMI for women was 508 per 100,000 vs. 371 per 100,000 in men. For 2004 age adjusted mortality rate from STEMI for women was 347 per 100,000 vs. 262 per 100,000 in men p< 0.001). For 1988, age adjusted mortality rate from STEMI for Caucasians was 412 per 100,000 vs. 521 per 100,000 in African Americans. For 2004, age adjusted mortality rate from STEMI for Caucasians was 277 per 100,000 vs. 447 per 100,000 in African Americans, p< 0.001, see figures ). Conclusion: Age adjusted mortality from acute STEMI has significantly declined over the last decade regardless of gender race with persistent higher mortality rate in women and African Americans over the years.

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