Abstract 5287: Recent trends in racial and regional disparities in cervical cancer incidence and mortality

Abstract

Abstract Background: Although black and Hispanic women experienced greater cervical cancer rate reduction in recent years, they continue to have higher incidence rates than whites. Great variations also exist among geographic regions of the US, with the South having both the highest incidence and mortality rates compared to other regions. The present study explores the question of whether living in the South is associated with greater racial disparity in cervical cancer incidence and mortality by examining race- and region-specific rates and the trend between 2000 and 2012. Methods: The Surveillance, Epidemiology, and End Results (SEER) 18 Program data was used. Incidence and mortality rates, annual percent changes, and disparity ratios of cervical cancer were calculated using SEER*Stat software and Joinpoint regression for four groups: US14-Non-Hispanic White (NHW), US14-Non-Hispanic Black (NHB), South-NHW, and South-NHB, where the South included 4 registries from Georgia and Louisiana. Results: The incidence and mortality rates were much higher among NHB women compared to NHW in the South and the US. The degree of racial disparities between NHB and NHW women was greater in terms of mortality rates than incidence rates. For all age groups, NHB women in the South consistently had higher incidence rates than NHB women in the US14 region. The mortality disparity ratios was highest among NHB women, followed by NHW women in the South, NHW women in US14, and finally NHB women in the South. Conclusions: Although racial disparity has been narrowed in recent years, there has been little change or even a growing gap between white women in the South and their counterparts in the US14 region. Age-specific analysis further indicated that the emerging regional gap observed among white women might be attributable to the excess number of new cases and deaths among young women. Citation Format: Wonsuk Yoo, Sangmi Kim, Steven Coughlin, Sejong Bae, Edward Partridge, Warner Huh, Sarah Dilley, Yunmi Chung. Recent trends in racial and regional disparities in cervical cancer incidence and mortality [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5287. doi:10.1158/1538-7445.AM2017-5287