Abstract 516: Protein Energy Undernutrition Is Associated With Increased Mortality In Patients Admitted For Abdominal Aortic Aneurysm Rupture.

Abstract

Objectives: Abdominal Aortic Aneurysm rupture is a surgical emergency associated with increased morbidity and mortality. Our study sought to estimate the impact of protein energy undernutrition (PEU) on the clinical outcome of patients admitted for abdominal aortic aneurysm rupture. Methods: Using the 2019 National Inpatients Sample Database, NIS was searched for adults with abdominal aortic aneurysm rupture as a principal diagnosis with or without PEU as a secondary diagnosis using ICD- 10 codes. Outcomes were in-hospital mortality, acute kidney injury (AKI), cardiogenic shock, CVA, myocardial infarction (MI), cardiac tamponade, acute hypoxic respiratory failure, intraoperative and post-procedure complications, and acute mesenteric ischemia. Results: 3,880 patients were admitted for abdominal aortic aneurysm rupture. Of those, 13% had a history of protein energy undernutrition. Patients with PEU had an increase in in-hospital mortality (p=0.0064) which was statistically significant. There was an increased rate of acute kidney injury (p<0.0001), acute mesenteric ischemia (p=0.0005), intraoperative and post-procedure complication (p<0.0001), and acute hypoxic respiratory failure (0.0034). Patients with PEU also had an increased length of hospital stay (18 days, 95% CI 15 - 21days VS 6 days, 95% CI 6 - 7) and hospital charges ($437,070.8, 95% CI $373,662.5 - $500,479.1 VS $ 200,328.1 95% CI, $184,811.6 - $217,844.6). However, there was no difference in the rate of cardiogenic shock (p=0.0812), cardiac tamponade (p=0.5813), and myocardial infarction (p=0.3389) Conclusion: Per this study, Protein Energy Undernutrition is associated with increased mortality when compared to the general population admitted for abdominal aortic aneurysms. Early identification and prevention of PEU can reduce mortality associated with abdominal aortic aneurysm rupture.