ABSTRACT 388

Abstract

Background and aims: Two types of NRS are commonly used in pediatric population:non-invasive continuous positive airway pressure (nCPAP) and non-invasive pressure support ventilation (PS-NIV),they have been used for similar indications. Aims: Aim of this study to compare the use of n-CPAP with PS-NIV in a pediatric intensive care unit at tertiary hospital to understanding the effectiveness of NRS therapy in a particular proportion of children require escalation therapy, and how to recognize those who require more advanced respiratory support by using bed side monitor data together with arterial blood gas (respiratory score and hypoxic score). Methods: This was retrospective observation study at period January 2012 till June 2013 at PICU Elkhadra Hospital Tripoli-Libya; data were collected on all children who were managed at PICU from PICU data record. The patients who were not improved after 2hrs,4hrs from study required invasive respiratory support and mechanical ventilation. Results: As the first mode NRS, 27 children received nCPA, and 28 received PS-NIV.For patients (14.8%) received nCPAP required intubation and mechanical ventilation compared with children with PS-NIV (14.2%)required intubation and MV. The need to escalation to mechanical ventilator at 2 hrs,4 hrs from the starting of NRS could be predicted by failure of normalization of respiratory score and hypoxic score. PS-NIV group has lower hypoxic score than nCPAP group p<0.001 and older p<0.004 respectively. Conclusions: PS-NIV is effective NRS for older children with sever respiratory distress.