ABSTRACT 360

Abstract

Background and aims: Benign epilepsies during infancy are characterized with a normal development before onset and a benign outcome. There is a need for standardized tests to evaluate the detailed intellectual and/or educational outcome of patients. Denver Developmental Screening Test is appropriate for ages between 0 and 72 months, and evaluates fine motor and gross motor skills, language, and adaptive personal/social skills. The developmental outcome scores are set for these four skills and total development. Aims: We aimed to investigate the neurocognitive outcome in children with benign infantile seizures. Methods: The neurologic outcome of children with benign infantile seizures were reevaluated with Denver developmental screening test and neurologic examination. The parent of each participant signed an informed consent form and the study was approved by the Ethics Committee of Zeynep Kamil Maternity and Childrens’ Training and Research Hospital. Results: Forty-two patients were evaluated. Neurologic examinations were normal in all children. Fine motor and gross motor skills, language and adaptive personal/social skills were near-normal in all patients with benign familial infantile seizures. Delay in language parameters were recorded in two patients with Benign non-familial infantile seizures. Language parameters were recorded as borderline in one patient and the other patient had near-normal gross motor skills, borderline adaptive personal/social skills and fine motor skills, significant delay in language parameters. Both patients with pathologic signs were male. Conclusions: Psychosocial and cognitive development of infants should be closely monitored. Language skills should be thoroughly evaluated with detailed neurocognitive screening tests in patients with benign non-familial infantile seizures.