Abstract 3462: Gender differences in dietary behavior and urinary gallic acid concentrations in racial minorities in New York City

Abstract

Abstract Nutrition is important for cancer prevention. Previous research has found that socioeconomic factors may affect access to a healthy diet, which may impact the risk of cancer. To investigate this association, we assessed dietary behavior and the urinary concentrations of gallic acid, an antioxidant found in various fruits and vegetables, in racial minorities in New York City. Ninety-one (91) participants were recruited from a senior center in East Harlem, New York City, a racially diverse and underserved community. A National Institute of Health (NIH) - validated diet survey questionnaire was used to collect dietary behavior data. Demographic and cancer information were also collected. All 91 participants completed the survey and forty-five (45) participants provided urine samples for gallic acid analysis. Associations between demographic factors and the intake of certain foods were assessed. Gender differences were significantly associated with dietary behavior and urinary gallic acid concentrations. Female participants had a higher daily intake of fruits compared to male participants (p<0.05). Additionally, female participants had significantly higher urinary gallic acid concentrations compared to male participants (p<0.05). Other associations were also observed. Age was negatively associated with the quantity of french fries/fried potatoes and white potatoes intake (p<0.05), while positively associated with frequency of fruit intake (p<0.05). Furthermore, Asian race was associated with a higher frequency of fruit intake (p<0.05), compared to other races. Among all recruited participants, we collected information on three cancer cases. Compared to non-cancer cases, participants with cancer reported a significantly lower fruit intake quantity (p<0.05). In a multivariate analysis, we observed a significant association between fruit intake quantity and urinary gallic acid concentration (p<0.05) after controlling for income. Our findings suggest that gender differences in dietary behavior and urinary gallic acid concentration may explain some of the gender differences in cancer incidence and prevalence observed in racial minority groups. Citation Format: Cristina Zambrano, Wenyue Lu, Cicely Johnson, Maayan Beeber, April Panitz, Safa Ibrahim, Marilyn Fraser, Grace Ma, Khursheed Navder, Ming-Chin Yeh, Olorunseun Ogunwobi. Gender differences in dietary behavior and urinary gallic acid concentrations in racial minorities in New York City [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 3462.